This Potion Permit Potions Guide will tell you how to brew Potions, how to unlock more Potions, and how to solve those tricky Task Potion puzzles!
How to Make Potions in Potion Permit
Making Potion Permit Potions isn't all that difficult -- think of it like a simple puzzle game where you can collect the pieces by exploring. Here's what you have to do:
- Gather Materials in the wilderness.
- Go to the Cauldron.
- Select a Potion you'd like to make.
- Place Materials on the grid in the Cauldron until it is full.
- Materials must fit exactly in the grid -- you cannot overflow outside of it.
- Brew the Potion.
- Once you've brewed a Potion 5 times, you can save a specific Potion recipe for quicker crafting.
What Does 'Add to Recipe' Do in Potion Permit?
The "Add to Recipe" feature in Potion Permit is unlocked after you've brewed a specific Potion a total of five times. On the fifth time, you can press the "Add to Recipe" button and it will save that exact Recipe for easier Potion brewing in the future.
After you've added a Recipe, you can brew that Recipe (or any other button you've saved) by pressing the indicated button on the bottom-right of the screen when you have a Potion Recipe highlighted. (For example, press X on an Xbox controller, and not A.) That will bring up a list of all of the Recipes you've saved. You can then brew as many of that Potion as you want in one action.
You can save a total of 3 Recipes. If you try to save a fourth Recipe, you will be prompted to replace one of your existing Potion Recipes.
How to Unlock More Potions in Potion Permit
You can unlock more Potions by progressing through the game and curing the pollution in the Meadow Range, Glaze Iceberg, and Barren Wasteland.
As you explore more of the world and solve more problems, the Medical Association will visit you and test your knowledge by requiring you to brew a Potion (and possibly Research it first). Successfully completing this test will unlock the next Tier of 5 Potions.
The sole exception to this rule are the Serums; you can only gain access to those by upgrading the Clinic.

Potion Permit Potion List
Here is a list of all of the Potion Permit Potions you can unlock in the game.
Tier 1 Potions
Neutralizing Herbal Balm
- Cures - Itchiness
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 140 G
Relaxing Balm
- Cures - Rashes
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 135 G
Wound Cleanser
- Cures - Bruises
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 135 G
Sun Drops
- Cures - Clammy Patches
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 150 G
Violet Mist
- Cures - Lumps
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 150 G
Basic Serum
- Cures - Automatically Diagnoses Tier 1 Diseases
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 125 G
Tier 2 Potions
Cerulean Scrub
- Cures - Dryness
- Allowed Elements - Water, Wind
- Sells for - 220 G
Peppers Ointment
- Cures - Stiffness
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 215 G
Popping Aid
- Cures - Blisters
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 215 G
Alacrity Concoction
- Cures - Swelling
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 225 G
Twirl Solution
- Cures - Swelling
- Allowed Elements - Fire, Water, Wind, Earth
- Sells for - 225 G
Intermediate Serum
- Cures - Automatically Diagnoses Tier 2 Diseases
- Allowed Elements - Fire, Wind, Earth
- Sells for - 215 G
Tier 3 Potions
Cooling Spray
- Cures - Numbness
- Allowed Elements - Water, Wind, Earth
- Sells for - 350 G
Freezing Draught
- Cures - Cramps
- Allowed Elements - Fire, Water, Wind
- Sells for - 330 G
Rejuvenating Tears
- Cures - Cramps
- Allowed Elements - Fire, Water, Wind
- Sells for - 330 G
Thunder Kiss
- Cures - Tingling
- Allowed Elements - Water, Wind, Earth
- Sells for - 350 G
Vision Ward
- Cures - Blurred Vision
- Allowed Elements - Fire, Wind, Earth
- Sells for - 320 G
Advanced Serum
- Cures - Automatically Diagnoses Tier 3 Diseases
- Allowed Elements - Water, Wind, Earth
- Sells for - 320 G
Tier 4 Potions
Beat Reagent
- Cures - Low Heart Rate
- Allowed Elements - Water, Wind, Earth
- Sells for - 500 G
Minty Goblet
- Cures - Burning
- Allowed Elements - Water, Wind, Earth
- Sells for - 470 G
Cloud Fairy
- Cures - Oxygen Depravation
- Allowed Elements - Fire, Wind, Earth
- Sells for - 485 G
Dark Tranquilizer
- Cures - Inflammation
- Allowed Elements - Fire, Water, Wind
- Sells for - 485 G
Calming Wind
- Cures - High Heart Rate
- Allowed Elements - Fire, Water, Earth
- Sells for - 490 G
Task-Specific Potions
These Potion Permit Potions are only crafted a single time in order to complete a Task. Task-specific Potions are typically more challenging to make than standard Potions.
The following is a gallery of possible solutions for crafting these Potions. Bear in mind that these are not the only ways to make them.
Angel Wine
Appetite Suppressor
Blade Tonic
Blue Blood
Bone Enhancer
Clear Potion
Draconic Temper
Energizer
Fancy Aromatic
Fiery Ointment
Fortified Bone Broth
Frostmite Repellent
Fungi Duster
Glowing Purified Water
Gunpowder
Heat Paste
Herbal Wax
Iris Vial
Liquid Fertilizer
Maggot Removal
Metal Rust Gel
Moonbrine
Moss Crusher
Pungent Draught
Relaxing Soother
Scalp Tonic
Slime Kisser
Soil Fertilizer
Stomach Cleanser
Sun Elixir
Sweet Crystals
Sweet Slumber
Tongue Cooler
Weight Enhancer
White Breeze
Thanks for reading our Potion Permit Potions Guide. Make sure to check out our other guides below!
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