If you're at this point in Blue Prince you'll have likely managed to unlock all of the outside additions, reach Room 46, gather all of the Red Letters and solve the Sanctum Keys. If any of those sound confusing to you then turn back now.
If you have completed all of the above and are interested in seeing what's at the far end of the tunnel then you've come to the right place. This is a multipart quest and along the way we'll give you hints to point you in the right direction.
Gain The Ability To Remove Boxes
Hint #1 - You used "A New Clue" to discover two of the Microchips, there's likely more hidden in there for you
Hint #2 - Find out what numbers X, Y, Z, A, B, C are by reading the signs on each page of "A New Clue"
Hint #3 - Follow the guide to find different colored books with Pages and Words that can be represented by X, Y, Z, A, B, C and follow the instructions

Remove The Boxes
By going to the Laboratory you can now connect to the Skyna Servers and download a new package of Laboratory experiments. Once of these new experiment conditions includes a result of removing a box from the tunnel.
There are upwards of 40 boxes (not an exact count) so you may need to spend a few days repeating this process to start an experiment, hope that you get one that will remove boxes, and then perform that experiment as many times as you can.
Past the Boxes
Once all (or at least the vast majority) of boxes has been removed you'll get access to a new room at the end of the hallway. This is a series of rooms that you'll need to complete certain criteria to open. The doors require, in order: Basement Key -> Keycard -> Super Hammer -> Red Boiler Room Box Active -> Fire Starting Tool
This will lead you to a large door with a Blue Holly symbol on it… and from there, I'm still discovering what to do next but this will also likely be the end of my guides. If you're wanting to go deeper, work with a group of friends or join the official discord where we're sure they're seeking the next solution. There's plenty more puzzles after this one...